Article

Aging-associated endolysosomal decline drives inflammaging and neurodegeneration through the STING-IFN-I axis

2026-03-18

Abstract excerpt

All animals age. However, aging is a heterogeneous process and individual organisms age differently. Moreover, within the same organism, cells or organs do not age at the same time or speed. For instance, although neurodegeneration is a key trait of aging, neurological symptoms normally manifest long after multiple indicators of aging in peripheral tissues. The genetic determinants of aging remain poorly understoo...

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Literature Corpus work: 7dfc61f7-b859-561c-b100-988ddd7b9f4b
DOI: 10.64898/2026.03.15.711864

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