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Telomere-targeted medicine: Bridging molecular mechanisms and clinical applications in age-related diseases

12 Aug 2025

Abstract excerpt

Telomeres, the nucleoprotein structures at the ends of chromosomes, have emerged as critical regulators of cellular aging and key contributors to the pathogenesis of age-related diseases. This comprehensive review examines the evolution of telomere biology from fundamental research to therapeutic applications, analyzing molecular mechanisms of telomere dysfunction across diverse disease categories, including...

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Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40812670
DOI: 10.1016/j.lfs.2025.123904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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