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Article

The STING1 network regulates autophagy and cell death

2 Jun 2021

Abstract excerpt

Cell death and immune response are at the core of life. In past decades, the endoplasmic reticulum (ER) protein STING1 (also known as STING or TMEM173) was found to play a fundamental role in the production of type I interferons (IFNs) and pro-inflammatory cytokines in response to DNA derived from invading microbial pathogens or damaged hosts by activating multiple transcription factors. In addition to this...

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PMID: 34078874
DOI: 10.1038/s41392-021-00613-4

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