Article

Single molecule DNA methylation and hydroxymethylation reveal unique epigenetic identity profiles of T helper cells

2023-02-04

Abstract excerpt

Both identity and plasticity of CD4 T helper (Th) cells are regulated in part by epigenetic mechanisms. However, a method that reliably and readily profiles DNA base modifications is still needed to finely study Th cell differentiation. Cytosine methylation (5mC) and cytosine hydroxymethylation (5hmC) are DNA modifications that identify stable cell phenotypes but their potential to characterize intermediate cell t...

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Literature Corpus work: 7d37a311-1c36-5456-82cd-581f087abba8
DOI: 10.1101/2023.02.03.527091

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