Article

Inferring cell-type-specific causal gene regulatory networks during human neurogenesis

2022-04-25

Abstract excerpt

<h4>Background</h4> Genetic variation influences both chromatin accessibility, assessed in chromatin accessibility quantitative trait loci (caQTL) studies, and gene expression, assessed in expression QTL (eQTL) studies. Genetic variants can impact either nearby genes (local eQTLs) or distal genes (trans eQTLs). Colocalization between caQTL and eQTL, or local- and distant-eQTLs suggests that they share causal vari...

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Literature Corpus work: 1ba9a3ad-c69e-52f5-a35f-46aebbafc977
DOI: 10.1101/2022.04.25.488920

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