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Single‐cell transcriptomes reveal heterogeneity of high‐grade serous ovarian carcinoma

1 Aug 2021

Abstract excerpt

BACKGROUND: High-grade serous ovarian carcinoma (HGSOC) is the most common and aggressive histotype of epithelial ovarian cancer. The heterogeneity and molecular basis of this disease remain incompletely understood. METHODS: To address this question, we have performed a single-cell transcriptomics analysis of matched primary and metastatic HGSOC samples. RESULTS: A total of 13 571 cells are categorized into six...

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PMID: 34459128
DOI: 10.1002/ctm2.500

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