Article

Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions

2023-09-04

Abstract excerpt

<h4>ABSTRACT</h4> The mRNA 5’-cap structure removal by the decapping enzyme DCP2 is a critical step in gene regulation. While DCP2 is the catalytic subunit in the decapping complex, its activity is strongly enhanced by multiple factors, particularly DCP1, which is the major activator in yeast. However, the precise role of DCP1 in metazoans has yet to be fully elucidated. Moreover, in humans, the specific biologic...

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Literature Corpus work: 7cccb8eb-14f7-5cbf-9f38-1e44e9654840
DOI: 10.1101/2023.09.04.556219

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