Article
The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1.
The EMBO journal - 3 Jun 2002
Fischer Nicole, Weis Karsten
Abstract excerpt
An important control step in the regulation of cytoplasmic mRNA turnover is the removal of the m(7)G cap structure at the 5' end of the message. Here, we describe the functional characterization of Dhh1, a highly conserved member of the family of DEAD box-containing proteins, as a regulator of mRNA decapping in Saccharomyces cerevisiae. Dhh1 is a cytoplasmic protein and is shown to be in a complex with the mRNA...
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