Article

Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b

2023-10-19

Abstract excerpt

Eukaryotic gene expression is regulated at both the transcriptional and post-transcriptional levels, with disruption of regulation contributing significantly to human diseases. In particular, the 5’ m7G mRNA cap is the central node in post-transcriptional regulation, participating in both mRNA stabilization and translation efficiency. DCP1a and DCP1b are paralogous cofactor proteins of the major mRNA cap hydrolase...

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Literature Corpus work: 7d5431e9-11be-5957-b110-12922b8a2698
DOI: 10.1101/2023.10.19.563039

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