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Article

Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow.

Blood - 15 Oct 2008

Palendira Umaimainthan, Chinn Rosanna, Raza Wajid, Piper Karen, Pratt Guy, Machado Lee, Bell Andrew, Khan Naeem, Hislop Andrew D, Steyn Richard, Rickinson Alan B, Buckley Christopher D, Moss Paul

Abstract excerpt

The bone marrow plays a unique role within the immune system. We compared the phenotype and function of virus-specific CD8(+) T cells from matched samples of human peripheral blood and bone marrow. Analysis of virus-specific memory CD8(+) T cells showed widely divergent partition of antigen-specific populations between blood and bone marrow. T cells specific for Epstein-Barr virus (EBV) lytic antigens were...

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Identifiers

PMID: 18635810
DOI: 10.1182/blood-2008-02-138040

Genes

CCR5
CXCR6
CXCR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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