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Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow

1 Dec 2000

Abstract excerpt

Bone marrow stem cells give rise to a variety of hematopoietic lineages and repopulate the blood throughout adult life. We show that, in a strain of mice incapable of developing cells of the myeloid and lymphoid lineages, transplanted adult bone marrow cells migrated into the brain and differentiated into cells that expressed neuron-specific antigens. These findings raise the possibility that bone marrow-derived...

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Identifiers

PMID: 11099419
DOI: 10.1126/science.290.5497.1779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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