Article

BET Protein Inhibition Evidently Enhances Sensitivity to PI3K/mTOR Dual Inhibition in Intrahepatic Cholangiocarcinoma

2021-06-21

Abstract excerpt

<h4>Background: </h4> & Aims: Intrahepatic cholangiocarcinoma (ICC), the second most common primary liver cancer, is a fatal malignancy with a poor prognosis. Molecular targeted therapy is a promising treatment strategy. However, resistance to molecular-targeted therapy is inevitable and represents a major clinical challenge. Our objective was to provide a novel and efficient therapeutic strategy in treating prima...

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Literature Corpus work: 7bf3f0d1-2796-57bb-a4ff-7fc5dccf468b
DOI: 10.21203/rs.3.rs-616430/v1

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