Article

AURKB activates EMT through PI3K/AKT signaling axis to promote ICC progression

2023-02-13

Abstract excerpt

Intrahepatic cholangiocarcinoma (ICC) is a fatal disease and the molecular mechanism of its progression is unknown. Aurora Kinase B (AURKB) is a central regulator of chromosome separation and cytokinesis and is abnormally expressed in a variety of cancer cells. This research aimed to explore the effect of AURKB in occurrence and metastasis of ICC. We found that AURKB showed a progressive up-regulation pattern from...

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Literature Corpus work: b4ee2d7e-863b-5dea-a86d-811e8acedf0e
DOI: 10.21203/rs.3.rs-2532778/v1

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