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Article

Altered Expression of Hippo Signaling Pathway Molecules in Intrahepatic Cholangiocarcinoma

1 Jan 2017

Abstract excerpt

OBJECTIVE: MOB1, a core component of the Hippo signaling pathway, suppresses cell proliferation, and MOB1 liver conditional knockout mice develop intrahepatic cholangiocarcinoma (ICC). However, its clinical significance in human ICC has not been established. The aim of this study was to characterize protein levels and the role of Hippo and TGF pathways in ICCs. METHODS: The protein levels of yes-associated...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 28448997
DOI: 10.1159/000463390

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