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Article

AURKB activates EMT through PI3K/AKT signaling axis to promote ICC progression

15 Jun 2023

Abstract excerpt

Intrahepatic cholangiocarcinoma (ICC) is a fatal disease and the molecular mechanism of its progression remains unknown. Aurora Kinase B (AURKB) is a central regulator of chromosome separation and cytokinesis and is abnormally expressed in a variety of cancer cells. This research aimed to explore the effect of AURKB in occurrence and metastasis of ICC. We found that AURKB showed a progressive up-regulation...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 37318676
DOI: 10.1007/s12672-023-00707-1

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