Article

TBC1D23-AAVR Interaction Drives Endosome-to-TGN Trafficking Required for rAAV Transduction

2026-06-03

Abstract excerpt

The adeno-associated virus receptor (AAVR; also known as KIAA0319L) is the proteinaceous receptor required for the transduction of multi-serotype adeno-associated viruses (AAVs). While the extracellular polycystic kidney disease (PKD) domains of AAVR directly bind AAV capsids, the function of its C-terminal cytosolic domain (AAVR-C) in governing AAV internalization and intracellular trafficking remains undefined....

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Literature Corpus work: 7bb874d5-c0ac-5cf0-b325-3e6d11918e5f
DOI: 10.64898/2026.06.02.729721

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