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Article

DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects

2020-05-02

Abstract excerpt

<h4>Background</h4> Epidemiological studies suggest that paternal obesity may increase the risk of fathering small for gestational age offspring. Studies in non-human mammals suggest that such associations could be mediated by DNA methylation changes in spermatozoa that influence offspring development in utero. Human obesity is associated with differential DNA methylation in peripheral blood. It is unclear, howev...

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Literature Corpus work
7b862780-de86-50a7-a286-4b7872ec3aad
DOI
10.1101/2020.05.01.072934
Open publication

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DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effectsDOI 10.1101/2020.05.01.072934
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