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Article

Male obesity impacts DNA methylation reprogramming in sperm

25 Jan 2021

Abstract excerpt

BACKGROUND: Male obesity has profound effects on morbidity and mortality, but relatively little is known about the impact of obesity on gametes and the potential for adverse effects of male obesity to be passed to the next generation. DNA methylation contributes to gene regulation and is erased and re-established during gametogenesis. Throughout post-pubertal spermatogenesis, there are continual needs to both...

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Share to Epigenetics and DNA Methylation
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sperm and Testicular Function

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PMID: 33494820
DOI: 10.1186/s13148-020-00997-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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