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Article

Paternal obesity induces changes in sperm chromatin accessibility and has a mild effect on offspring metabolic health

1 Jul 2024

Abstract excerpt

The increasing global burden of metabolic disorders including obesity and diabetes necessitates a comprehensive understanding of their etiology, which not only encompasses genetic and environmental factors but also parental influence. Recent evidence has unveiled paternal obesity as a contributing factor to offspring's metabolic health via sperm epigenetic modifications. In this study, we investigated the impact...

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Share to Epigenetics and DNA Methylation
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39100496
DOI: 10.1016/j.heliyon.2024.e34043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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