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Article

Male obesity effects on sperm and next-generation cord blood DNA methylation

27 Jun 2019

Abstract excerpt

The prevalence of metabolic disorders, in particular obesity has dramatically increased worldwide. Genetic variants explain only a minor part of the obesity epidemic induced by physical inactivity and over-nutrition. Epidemiological studies in humans and animal models indicate that epigenetic changes associated with adverse parental and/or intrauterine factors may contribute to the missing heritability of...

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PMID: 31246962
DOI: 10.1371/journal.pone.0218615

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