Article

Altered sperm DNA methylation in overweight men associates transposable element regulation to paternal origins of disease risk in children

2025-09-17

Abstract excerpt

The occurrence of childhood neurodevelopmental disorders has been steadily increasing for decades yet we have little understanding of modes of inheritance implicated in these diseases. Epidemiology studies have revealed an association between an elevated paternal BMI and an increased risk for autism in children, suggesting non-genetic modes of inheritance may be involved. Epigenetic marks, like DNA methylation at...

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Literature Corpus work: 3220f9a7-f2db-5fa1-8279-d558c15c1c6f
DOI: 10.1101/2025.09.15.675616

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