Back to search

Article

Genetic variation associated with human longevity and Alzheimer’s disease risk act through microglia and oligodendrocyte cross-talk

2023-04-06

Abstract excerpt

<title>Abstract</title><p>Ageing is the greatest global healthcare challenge, as it underlies age-related functional decline and is the primary risk factor for a range of common diseases, including neurodegenerative conditions such as Alzheimer’s disease (AD). However, the molecular mechanisms defining chronological age versus biological age, and how these underlie AD pathogenesis, are not well understood. The obj...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7b6295b3-754d-52eb-9ed8-e7c9508cb071
DOI
10.21203/rs.3.rs-2752922/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic variation associated with human longevity and Alzheimer’s disease risk act through microglia and oligodendrocyte cross-talkDOI 10.21203/rs.3.rs-2752922/v1
Select a neighboring publication to make it the new centre.