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Article

Largest GWAS (N=1,126,563) of Alzheimer’s Disease Implicates Microglia and Immune Cells

2020-11-23

Abstract excerpt

<h4>Summary</h4> Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts for 50-70% of dementia cases 1 . Late-onset Alzheimer’s disease is caused by a combination of many genetic variants with small effect sizes and environmental influences. Currently, only a fraction of the genetic variants underlying Alzheimer’s disease have been identified 2,3 . Here we show that increased sam...

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Identifiers and source

Literature Corpus work
806010ef-b323-549f-8609-da99d7a50031
DOI
10.1101/2020.11.20.20235275
Open publication

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Largest GWAS (N=1,126,563) of Alzheimer’s Disease Implicates Microglia and Immune CellsDOI 10.1101/2020.11.20.20235275
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