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Genetic variation associated with human longevity and Alzheimer's disease risk act through microglia and oligodendrocyte cross-talk

2023-04-03

Abstract excerpt

Ageing is the greatest global healthcare challenge, as it underlies age-related functional decline and is the primary risk factor for a range of common diseases, including neurodegenerative conditions such as Alzheimer's disease (AD). However, the molecular mechanisms defining chronological age versus biological age, and how these underlie AD pathogenesis, are not well understood. The objective of this study was t...

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Literature Corpus work
084e1b36-93c2-5630-ab24-c4efb7c270e9
DOI
10.1101/2023.03.30.23287975
Open publication

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Genetic variation associated with human longevity and Alzheimer's disease risk act through microglia and oligodendrocyte cross-talkDOI 10.1101/2023.03.30.23287975
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