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Benchmarking long-read RNA-sequencing technologies with <i>LongBench:</i> a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches

2025-09-12

Abstract excerpt

Long-read RNA sequencing enables full-length transcript profiling and improved isoform resolution, but variable platforms and evolving chemistries demand careful benchmarking for reliable application. We present LongBench , a matched, multi-platform reference dataset spanning bulk, single-cell, and single-nucleus transcriptomics across eight human lung cancer cell lines with synthetic spike-in controls. LongBenc...

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Literature Corpus work: 7b4a0c17-ad13-52d3-b56b-fe2d7ad63b40
DOI: 10.1101/2025.09.11.675724

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