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Toward Best Practice in Identifying Subtle Differential Expression with RNA-seq: A Real-World Multi-Center Benchmarking Study Using Quartet and MAQC Reference Materials

2024-01-09

Abstract excerpt

<title>Abstract</title> <p>Translating RNA-seq into clinical diagnostics requires ensuring the reliability of detecting clinically relevant subtle differential expressions, such as those between different disease subtypes or stages. Moreover, cross-laboratory reproducibility and consistency under diverse experimental and bioinformatics workflows urgently need to be addressed. As part of the Quartet project, we pr...

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Literature Corpus work: f9820e9d-16f3-5b14-8d6c-6b938f89c721
DOI: 10.21203/rs.3.rs-3718519/v1

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