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Article

Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer.

Nature communications - 12 Aug 2024

Byrne Ashley, Le Daniel, Sereti Kostianna, Menon Hari, Vaidya Samir, Patel Neha, Lund Jessica, Xavier-Magalhães Ana, Shi Minyi, Liang Yuxin, Sterne-Weiler Timothy, Modrusan Zora, Stephenson William

Abstract excerpt

Single-cell RNA sequencing predominantly employs short-read sequencing to characterize cell types, states and dynamics; however, it is inadequate for comprehensive characterization of RNA isoforms. Long-read sequencing technologies enable single-cell RNA isoform detection but are hampered by lower throughput and unintended sequencing of artifacts. Here we develop Single-cell Targeted Isoform Long-Read Sequencing...

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Share to Allelic Imbalance
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39134520
DOI: 10.1038/s41467-024-51252-6
PMCID: PMC11319652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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