Article

A ratio-based framework using Quartet reference materials for integrating long- and short-read RNA-seq

2025-12-03

Abstract excerpt

<title>Abstract</title> <p>Long-read RNA sequencing (lrRNA-seq) enables full-length transcript profiling but is confounded by technical batch effects that compromise quantification and prevent data integration across platforms, protocols, and laboratories. The lack of a transcriptome-wide biological ground truth has hindered objective benchmarking. To address these dual challenges, we leveraged certified Quartet...

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Literature Corpus work: 4159e766-ae9c-5851-9c45-849ca8de08db
DOI: 10.21203/rs.3.rs-8024543/v1

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