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R2C2: Improving nanopore read accuracy enables the sequencing of highly-multiplexed full-length single-cell cDNA

2018-06-04

Abstract excerpt

High-throughput short-read sequencing has revolutionized how transcriptomes are quantified and annotated. However, while Illumina short-read sequencers can be used to analyze entire transcriptomes down to the level of individual splicing events with great accuracy, they fall short of analyzing how these individual events are combined into complete RNA transcript isoforms. Because of this shortfall, long-read seque...

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Literature Corpus work
9fa5be1a-a0d3-5ef6-b321-d30b406545fe
DOI
10.1101/338020
Open publication

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R2C2: Improving nanopore read accuracy enables the sequencing of highly-multiplexed full-length single-cell cDNADOI 10.1101/338020
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