Article
Functional differences between type 1 and type 2 Epstein-Barr virus EBNA-2
2011-01-01
Abstract excerpt
Epstein-Barr virus (EBV) establishes a lifelong latent infection in the human host. In vitro EBV immortalises primary B lymphocytes giving rise to latently infected lymphoblastoid cell lines (LCLs). EBV strains are classified as type 1 or type 2 according to the sequence of the EBNA-2 gene, which expresses a transcription factor that induces viral and cell genes important for B cell proliferation. Type 1 EBV trans...
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Identifiers and source
- Literature Corpus work
- 7b2928c7-5e86-5d90-b2b7-fe31b11ac1cb
- DOI
- 10.25560/8997