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The Epstein-Barr Virus EBNA1 Protein

1 Jan 2012

Abstract excerpt

Epstein-Barr virus (EBV) is a widespread human herpes virus that immortalizes cells as part of its latent infection and is a causative agent in the development of several types of lymphomas and carcinomas. Replication and stable persistence of the EBV genomes in latent infection require the viral EBNA1 protein, which binds specific DNA sequences in the viral DNA. While the roles of EBNA1 were initially thought to...

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PMID: 24278697
DOI: 10.6064/2012/438204

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