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Screening and functional analysis of differentially expressed genes in EBV-transformed lymphoblasts

30 Mar 2012

Abstract excerpt

BACKGROUND: Epstain-Barr virus (EBV) can transform human B lymphocytes making them immortalized and inducing tumorigenic ability in vitro, but the molecular mechanisms remain unclear. The aim of the present study is to detect and analyze differentially expressed genes in two types of host cells, normal human lymphocytes and coupled EBV-transformed lymphoblasts in vitro using gene chips, and to screen the key...

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PMID: 22458412
DOI: 10.1186/1743-422x-9-77

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