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Article

Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor.

Journal of virology - 1 Apr 2016

Murata Takayuki, Noda Chieko, Narita Yohei, Watanabe Takahiro, Yoshida Masahiro, Ashio Keiji, Sato Yoshitaka, Goshima Fumi, Kanda Teru, Yoshiyama Hironori, Tsurumi Tatsuya, Kimura Hiroshi

Abstract excerpt

UNLABELLED: Latent membrane protein 1 (LMP1) is a major oncogene essential for primary B cell transformation by Epstein-Barr virus (EBV). Previous studies suggested that some transcription factors, such as PU.1, RBP-Jκ, NF-κB, and STAT, are involved in this expression, but the underlying mechanism is unclear. Here, we identified binding sites for PAX5, AP-2, and EBF in the proximal LMP1 promoter (ED-L1p). We...

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Identifiers

PMID: 26819314
DOI: 10.1128/JVI.03227-15
PMCID: PMC4810554

Genes

PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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