Article

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals

2021-06-07

Abstract excerpt

Impaired lung function is predictive of mortality and is a key component in the diagnosis of chronic obstructive pulmonary disease. Lung function has a strong genetic component but is also affected by environmental factors such as increased exposure to air pollution. How genetic factors and air pollution interact to affect lung function is however less understood. We conducted a genome-wide gene-air pollution inte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7a3149a1-0669-5738-bb25-7e299039ec6f
DOI: 10.1101/2021.06.03.21256376

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individualsDOI 10.1101/2021.06.03.21256376Read

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individualsSemantic proximity Read

Genetic susceptibility to respiratory health effects from outdoor air pollution: a structured narrative review.Semantic proximity Read

Air pollution, genetic susceptibility and risk of progression from asthma to COPD.Semantic proximity Read

Genome-wide analysis of gene and air pollution interactions on COPD in the CLSA cohort.Semantic proximity Read

Smoking Interaction with a Polygenic Risk Score for Reduced Lung FunctionSemantic proximity Read

Air Pollution, Genetic Factors, and the Risk of Lung Cancer: A Prospective Study in the UK Biobank.Semantic proximity Read

Air pollution and risk of chronic obstructed pulmonary disease: The modifying effect of genetic susceptibility and lifestyle.Semantic proximity Read

Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults?Semantic proximity Read

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung functionSemantic proximity Read

Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function.Semantic proximity Read

Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels.Semantic proximity Read

Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study.Semantic proximity Read