Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals

16 Dec 2021

Abstract excerpt

Impaired lung function is predictive of mortality and is a key component of chronic obstructive pulmonary disease. Lung function has a strong genetic component but is also affected by environmental factors such as increased exposure to air pollution, but the effect of their interactions is not well understood. To identify interactions between genetic variants and air pollution measures which affect COPD risk and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Air Quality and Health Impacts
Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to Glutathione Transferases and Polymorphisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34923368
DOI: 10.1016/j.envint.2021.107041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individualsPMID 34923368Read ↗

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individualsSemantic proximity Read ↗

Genome-wide analysis of gene and air pollution interactions on COPD in the CLSA cohort.Semantic proximity Read ↗

Genetic susceptibility to respiratory health effects from outdoor air pollution: a structured narrative review.Semantic proximity Read ↗

Air pollution, genetic susceptibility and risk of progression from asthma to COPD.Semantic proximity Read ↗

Air pollution and risk of chronic obstructed pulmonary disease: The modifying effect of genetic susceptibility and lifestyle.Semantic proximity Read ↗

Smoking Interaction with a Polygenic Risk Score for Reduced Lung FunctionSemantic proximity Read ↗

Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults?Semantic proximity Read ↗

Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function.Semantic proximity Read ↗

Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population.Semantic proximity Read ↗

The impact of PM2.5 on lung function and chronic respiratory diseases: insights from genetic evidence.Semantic proximity Read ↗

Air Pollution, Genetic Factors, and the Risk of Lung Cancer: A Prospective Study in the UK Biobank.Semantic proximity Read ↗

Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.