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Article

Genome-wide analysis of gene and air pollution interactions on COPD in the CLSA cohort.

Environmental research - 1 Mar 2026

Odimba Ugochukwu, Farrell Jamie, Sadatsafavi Mohsen, Jiang Xianta, Gao Zhiwei

Abstract excerpt

Ambient air pollution contributes to chronic obstructive pulmonary disease (COPD), but the genetic factors that may influence susceptibility remain poorly defined. We conducted a genome-wide interaction analysis to identify genetic markers that may modify the association between air pollution and COPD. We analyzed data from 16,839 Canadian Longitudinal Study of Aging participants, including spirometry,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41571064
DOI: 10.1016/j.envres.2026.123837

Genes

ADAMTS9
ADAMTSL3
CALM2
CEP72
CPO
DLG2
EPCAM
FASTKD2
SH3GL3
TPPP
WFDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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