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Article

Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function.

The American journal of clinical nutrition - 1 May 2024

Seo Jungkyun, Gaddis Nathan C, Patchen Bonnie K, Xu Jiayi, Barr R Graham, O'Connor George, Manichaikul Ani W, Gharib Sina A, Dupuis Josée, North Kari E, Cassano Patricia A, Hancock Dana B

Abstract excerpt

BACKGROUND: Higher 25-hydroxyvitamin D (25(OH)D) concentrations in serum has a positive association with pulmonary function. Investigating genome-wide interactions with 25(OH)D may reveal new biological insights into pulmonary function. OBJECTIVES: We aimed to identify novel genetic variants associated with pulmonary function by accounting for 25(OH)D interactions. METHODS: We included 211,264 participants from...

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Identifiers

PMID: 38484975
DOI: 10.1016/j.ajcnut.2024.03.007
PMCID: PMC11130669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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