Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Air Pollution, Genetic Factors, and the Risk of Lung Cancer: A Prospective Study in the UK Biobank.

American journal of respiratory and critical care medicine - 1 Oct 2021

Huang Yanqian, Zhu Meng, Ji Mengmeng, Fan Jingyi, Xie Junxing, Wei Xiaoxia, Jiang Xiangxiang, Xu Jing, Chen Liang, Yin Rong, Wang Yuzhuo, Dai Juncheng, Jin Guangfu, Xu Lin, Hu Zhibin, Ma Hongxia, Shen Hongbing

Abstract excerpt

Rationale: Both genetic and environmental factors contribute to lung cancer, but the degree to which air pollution modifies the impact of genetic susceptibility on lung cancer remains unknown. Objectives: To investigate whether air pollution and genetic factors jointly contribute to incident lung cancer. Methods: We analyzed data from 455,974 participants (53% women) without previous cancer at baseline in the UK...

Topics

Join the communities discussing this publication.

Air Pollutants
Air Pollution
Biological Specimen Banks
Environmental Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene-Environment Interaction

Particulate Matter

Proportional Hazards Models

Source

Identifiers

PMID: 34252012
DOI: 10.1164/rccm.202011-4063OC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Air Pollution, Genetic Factors, and the Risk of Lung Cancer: A Prospective Study in the UK Biobank.PMID 34252012Read ↗

Air pollution, genetic susceptibility and risk of progression from asthma to COPD.Semantic proximity Read ↗

Histological types of lung cancer attributable to fine particulate, smoking, and genetic susceptibility.Semantic proximity Read ↗

Air pollution and risk of chronic obstructed pulmonary disease: The modifying effect of genetic susceptibility and lifestyle.Semantic proximity Read ↗

Ambient air pollution, lifestyle, and genetic predisposition on all-cause and cause-specific mortality: A prospective cohort study.Semantic proximity Read ↗

Air pollutants, genetic susceptibility and risk of incident idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Ambient air pollution, genetic risk and telomere length in UK biobank.Semantic proximity Read ↗

Interplay of Polygenic Risk Score, Smoking Statuses, and Air Pollution on Lung Adenocarcinoma Risk in a Taiwanese Population.Semantic proximity Read ↗

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individualsSemantic proximity Read ↗

Exposure to Air Pollution, Genetic Susceptibility, and Psoriasis Risk in the UK.Semantic proximity Read ↗

Combined Effect of Air Pollution and Genetic Risk on Incident Cardiovascular Diseases.Semantic proximity Read ↗

Air pollution exposure modes, smoking and genetic risk with chronic respiratory diseases: a prospective study.Semantic proximity Read ↗

Air Pollution, Genetic Susceptibility, and Risk of Incident Systemic Lupus Erythematosus: A Prospective Cohort Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.