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Air pollution, genetic susceptibility and risk of progression from asthma to COPD.

Thorax - 15 Dec 2025

Li Guoxing, Zhang Ke, Yang Teng, Jin Jianbo, Guo Xinbiao, Cai Yutong Samuel, Huang Jing

Abstract excerpt

BACKGROUND: In the UK, an estimated 15% of asthma patients have concurrent chronic obstructive pulmonary disease (COPD), yet the underlying causes and mechanisms remain largely unexplored. This study aimed to investigate the roles of both ambient air pollution and genetic susceptibility in the progression from asthma to COPD. METHODS: 46 832 participants with asthma were recruited from the UK Biobank during the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40691049
DOI: 10.1136/thorax-2024-222871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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