Article
Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults?
Environment international - 1 Mar 2014
Thun Gian Andri, Imboden Medea, Künzli Nino, Rochat Thierry, Keidel Dirk, Haun Margot, Schindler Christian, Kronenberg Florian, Probst-Hensch Nicole M
Abstract excerpt
Improved air quality has been found associated with attenuated age-related decline in lung function. But whether genetic polymorphisms strongly associated with lung function play a modifying role in this attenuation process has so far not been investigated. We selected ten single nucleotide polymorphisms derived from the largest genome-wide association studies on lung function and examined whether they modified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
