Article
Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study.
Environmental health : a global access science source - 1 Dec 2013
Liao Shu-Yi, Lin Xihong, Christiani David C
Abstract excerpt
BACKGROUND: Previous studies in occupational exposure and lung function have focused only on the main effect of occupational exposure or genetics on lung function. Some disease-susceptible genes may be missed due to their low marginal effects, despite potential involvement in the disease process through interactions with the environment. Through comprehensive genome-wide gene-environment interaction studies, we...
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