Article

Developmental loci harbor clusters of accelerated regions that evolved independently in ape lineages

2017-11-28

Abstract excerpt

Some of the fastest evolving regions of the human genome are conserved non-coding elements with many human-specific DNA substitutions. These Human Accelerated Regions (HARs) are enriched nearby regulatory genes, and several HARs function as developmental enhancers. To investigate if this evolutionary signature is unique to humans, we quantified evidence of accelerated substitutions in conserved genomic elements ac...

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Literature Corpus work: 7a2902fc-993f-5c76-ac15-4ebfd778b879
DOI: 10.1101/226019

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