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Article

Fast-evolving noncoding sequences in the human genome.

Genome biology - 1 Jan 2007

Bird Christine P, Stranger Barbara E, Liu Maureen, Thomas Daryl J, Ingle Catherine E, Beazley Claude, Miller Webb, Hurles Matthew E, Dermitzakis Emmanouil T

Abstract excerpt

BACKGROUND: Gene regulation is considered one of the driving forces of evolution. Although protein-coding DNA sequences and RNA genes have been subject to recent evolutionary events in the human lineage, it has been hypothesized that the large phenotypic divergence between humans and chimpanzees has been driven mainly by changes in gene regulation rather than altered protein-coding gene sequences. Comparative...

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Identifiers

PMID: 17578567
DOI: 10.1186/gb-2007-8-6-r118
PMCID: PMC2394770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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