Article

A therapeutic small molecule lead enhances γ-oscillations and improves cognition/memory in Alzheimer’s disease model mice

2023-12-06

Abstract excerpt

<h4>Summary</h4> Brain rhythms provide the timing and concurrence of brain activity required for linking together neuronal ensembles engaged in specific tasks. In particular, the γ-oscillations (30-120 Hz) orchestrate neuronal circuits underlying cognitive processes and working memory. These oscillations are reduced in numerous neurological and psychiatric disorders, including early cognitive decline in Alzheimer...

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Literature Corpus work: 7a1d6cc4-cea9-5123-b251-0a444f4fe709
DOI: 10.1101/2023.12.04.569994

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