Article

Ketogenic diet or BHB improves epileptiform spikes, memory, survival in Alzheimer’s model

2017-05-09

Abstract excerpt

Links between epilepsy and Alzheimer’s disease (AD) are seen in both human patients and mouse models. Human patients with AD may commonly have subclinical epileptiform spikes (EP spikes) 1 , and overt epilepsy is associated with more rapid cognitive decline 2 . Mechanistic studies in mouse models of Alzheimer’s disease (AD) have shown that altered network activity and epileptiform spikes stem from dysfunctional...

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Literature Corpus work: 0da78d4c-7619-5601-a171-ebf7d25fd35d
DOI: 10.1101/136226

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