Article

<i>Toxoplasma gondii</i> importin α shows weak auto-inhibition

2022-10-06

Abstract excerpt

<h4>ABSTRACT</h4> Importin α is a nuclear transporter that binds to nuclear localization signals (NLSs), consisting of 7-20 positively charged amino acids found within cargo proteins. In addition to cargo binding, intramolecular interactions also occur within the importin α protein due to binding between the importin β-binding (IBB) domain and the NLS-binding sites, a phenomenon called auto-inhibition. The intera...

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Literature Corpus work: 79f5c876-623a-5d18-9313-f8dfcf825b4e
DOI: 10.1101/2022.10.06.510747

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