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Importin α inhibitors act against the differentiated stages of apicomplexan parasites <i>Plasmodium falciparum</i> and <i>Toxoplasma gondii</i>

2024-07-10

Abstract excerpt

Protozoan parasites of the phylum Apicomplexa, including Plasmodium falciparum and Toxoplasma gondii , cause widespread disease in humans. New drugs and protein targets are required for the treatment of these diseases, particularly therapies targeting multiple stages of the parasite life cycles. Nuclear import, carried out by the transporter’s importin (IMP) α and β subunits, is a valid target for the discovery...

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Literature Corpus work
47285475-44f6-5ce6-b7c0-6a4c03fdb3cd
DOI
10.1101/2024.07.10.602875
Open publication

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