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Origin and segregation of the human germline

2022-07-07

Abstract excerpt

Human germline-soma segregation occurs during weeks 2-3 in gastrulating embryos. While direct studies are hindered, here we investigate the dynamics of human primordial germ cell (PGCs) specification using in vitro models with temporally resolved single-cell transcriptomics and in-depth characterisation to in vivo datasets from human and non-human primates, including a 3D marmoset reference atlas. We elucidate the...

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Identifiers and source

Literature Corpus work
79ad6c06-a56a-58fc-a740-73d0ebf7aa38
DOI
10.1101/2022.07.06.498671
Open publication

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Origin and segregation of the human germlineDOI 10.1101/2022.07.06.498671
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