Article

Temporally resolved single cell transcriptomics in a human model of amniogenesis

2023-09-09

Abstract excerpt

Amniogenesis is triggered in a collection of pluripotent epiblast cells as the human embryo implants. To gain insights into the critical but poorly understood transcriptional machinery governing amnion fate determination, we examined the evolving transcriptome of a developing human pluripotent stem cell-derived amnion model at the single cell level. This analysis revealed several continuous amniotic fate progressi...

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Literature Corpus work: 3f69f1e5-c1a1-5442-a15e-0ea85bbdcf2b
DOI: 10.1101/2023.09.07.556553

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