Article

Integrated single-cell sequencing reveals principles of epigenetic regulation of human gastrulation and germ cell development in a 3D organoid model

2022-02-10

Abstract excerpt

The emergence of different cell types and the role of the epigenome in regulating transcription is a key yet understudied event during human gastrulation. Investigating these questions remain infeasible due to the lack of availability of embryos at these stages of development. Further, human gastrulation is marked by dynamic changes in cell states that are difficult to isolate at high purity, thereby making it cha...

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Literature Corpus work: f8f08dab-be3d-5c38-a8ba-d7f2c98741b3
DOI: 10.1101/2022.02.10.479957

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